Symbol: Name: ID: |
TLN2 talin 2 GFS:4657 |
Gene name: | TLN2 |
Chromosome: | 15q15-q21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0320, ILWEQ |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1917799 | Rat Genome Database ID: | RGD:1565416 |
HGNC ID: | HGNC:15447 | RefSeq IDs: | NM_015059 |
Entrez Gene ID: | 83660 | Ensembl Gene ID: | ENSG00000171914 |
VEGA IDs: | OTTHUMG00000133679 | UniProt ID: | Q9Y4G6 |
UCSC ID: | uc002alb.3 | OMIM ID: | 607349 |
Pubmed: | PMID9205841 PMID 11527381 | ||
CCDS IDs: | CCDSCCDS32261.1 |
This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity).
Products for TLN2 gene
Catalog | Product Name | Application | Company |
GFS:E04657 | talin 2; ELISA kit | ELISA | n/a |
GFS:A04657 | talin 2; Anti | ANTIBODIES | n/a |
GFS:P04657 | talin 2; Protien | Protien | n/a |