Symbol: Name: ID: |
TAC4 tachykinin 4 (hemokinin) GFS:5742 |
Gene name: | TAC4 |
Chromosome: | 17q21.33 |
Previous Symbols: | |
Previous Names: | |
Aliases: | HK-1, Pptc, PPT-C |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1931130 | Rat Genome Database ID: | RGD:628842 |
HGNC ID: | HGNC:16641 | RefSeq IDs: | NM_001077503 |
Entrez Gene ID: | 255061 | Ensembl Gene ID: | ENSG00000176358 |
VEGA IDs: | UniProt ID: | Q86UU9 | |
UCSC ID: | uc002ipo.1 | OMIM ID: | 607833 |
Pubmed: | PMID11062498 PMID 12383518 | ||
CCDS IDs: | CCDSCCDS42357.1 CCDS CCDS42358.1 CCDS CCDS42359.1 CCDS CCDS42360.1 CCDS CCDS45727.1 |
Tachykinin-4 is a protein that in humans is encoded by the TAC4 gene.
This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility .
Products for TAC4 gene
Catalog | Product Name | Application | Company |
GFS:E05742 | tachykinin 4 (hemokinin); ELISA kit | ELISA | n/a |
GFS:A05742 | tachykinin 4 (hemokinin); Anti | ANTIBODIES | n/a |
GFS:P05742 | tachykinin 4 (hemokinin); Protien | Protien | n/a |