Symbol: Name: ID: |
TACC2 transforming, acidic coiled-coil containing protein 2 GFS:1380 |
Gene name: | TACC2 |
Chromosome: | 10q26 |
Previous Symbols: | |
Previous Names: | |
Aliases: | AZU-1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1928899 | Rat Genome Database ID: | RGD:1303004 |
HGNC ID: | HGNC:11523 | RefSeq IDs: | NM_006997 |
Entrez Gene ID: | 10579 | Ensembl Gene ID: | ENSG00000138162 |
VEGA IDs: | OTTHUMG00000019181 | UniProt ID: | O95359 |
UCSC ID: | uc001lfv.2 | OMIM ID: | 605302 |
Pubmed: | PMID14767476 | ||
CCDS IDs: | CCDSCCDS7625.1 CCDS CCDS7626.1 CCDS CCDS7627.1 CCDS CCDS7628.1 |
Transforming acidic coiled-coil-containing protein 2 is a protein that in humans is encoded by the TACC2 gene. Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker.
Products for TACC2 gene
Catalog | Product Name | Application | Company |
GFS:E01380 | transforming, acidic coiled-coil containing protein 2; ELISA kit | ELISA | n/a |
GFS:A01380 | transforming, acidic coiled-coil containing protein 2; Anti | ANTIBODIES | n/a |
GFS:P01380 | transforming, acidic coiled-coil containing protein 2; Protien | Protien | n/a |