Symbol: Name: ID: |
STXBP2 syntaxin binding protein 2 GFS:1316 |
Gene name: | STXBP2 |
Chromosome: | 19p13.3-p13.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | UNC18B, Hunc18b |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107370 | Rat Genome Database ID: | RGD:619967 |
HGNC ID: | HGNC:11445 | RefSeq IDs: | NM_001127396 |
Entrez Gene ID: | 6813 | Ensembl Gene ID: | ENSG00000076944 |
VEGA IDs: | UniProt ID: | Q15833 | |
UCSC ID: | uc002mha.3 | OMIM ID: | 601717 |
Pubmed: | PMID8921365 | ||
CCDS IDs: | CCDSCCDS12181.1 CCDS CCDS45948.1 |
Syntaxin-binding protein 2 is a protein that in humans is encoded by the STXBP2 gene. This gene encodes a member of the STXBP/unc-18/SEC1 family. These genes are conserved across species from yeast to man, and are believed to be involved in protein trafficking from the golgi apparatus to the plasma membrane. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.
Products for STXBP2 gene
Catalog | Product Name | Application | Company |
GFS:E01316 | syntaxin binding protein 2; ELISA kit | ELISA | n/a |
GFS:A01316 | syntaxin binding protein 2; Anti | ANTIBODIES | n/a |
GFS:P01316 | syntaxin binding protein 2; Protien | Protien | n/a |