Symbol: Name: ID: |
STXBP1 syntaxin binding protein 1 GFS:1315 |
Gene name: | STXBP1 |
Chromosome: | 9q34.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | hUNC18, MUNC18-1, UNC18, rbSec1 |
Name Aliases: | syntaxin-binding protein 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107363 | Rat Genome Database ID: | RGD:3785 |
HGNC ID: | HGNC:11444 | RefSeq IDs: | NM_001032221 |
Entrez Gene ID: | 6812 | Ensembl Gene ID: | ENSG00000136854 |
VEGA IDs: | OTTHUMG00000020713 | UniProt ID: | P61764 |
UCSC ID: | uc004brk.2 | OMIM ID: | 602926 |
Pubmed: | PMID9545644 | ||
CCDS IDs: | CCDSCCDS6874.1 CCDS CCDS35146.1 |
Syntaxin-binding protein 1 is a protein that in humans is encoded by the STXBP1 gene. This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. [provided by RefSeq].
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
Products for STXBP1 gene
Catalog | Product Name | Application | Company |
GFS:E01315 | syntaxin binding protein 1; ELISA kit | ELISA | n/a |
GFS:A01315 | syntaxin binding protein 1; Anti | ANTIBODIES | n/a |
GFS:P01315 | syntaxin binding protein 1; Protien | Protien | n/a |