Symbol: Name: ID: |
SDC1 syndecan 1 GFS:580 |
Gene name: | SDC1 |
Chromosome: | 2p24.1 |
Previous Symbols: | SDC |
Previous Names: | |
Aliases: | CD138, syndecan, SYND1 |
Name Aliases: | syndecan proteoglycan 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1349162 | Rat Genome Database ID: | RGD:3648 |
HGNC ID: | HGNC:10658 | RefSeq IDs: | NM_001006946 |
Entrez Gene ID: | 6382 | Ensembl Gene ID: | ENSG00000115884 |
VEGA IDs: | OTTHUMG00000090751 | UniProt ID: | P18827 |
UCSC ID: | uc002rdo.1 | OMIM ID: | 186355 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS1697.1 |
Syndecan 1 is a protein which in humans is encoded by the SDC1 gene.The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq].
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix
Products for SDC1 gene
Catalog | Product Name | Application | Company |
GFS:E00580 | syndecan 1; ELISA kit | ELISA | n/a |
GFS:A00580 | syndecan 1; Anti | ANTIBODIES | n/a |
GFS:P00580 | syndecan 1; Protien | Protien | n/a |