Symbol: Name: ID: |
SFTPA2 surfactant protein A2 GFS:714 |
Gene name: | SFTPA2 |
Chromosome: | 10q22.3 |
Previous Symbols: | |
Previous Names: | surfactant, pulmonary-associated protein A2 |
Aliases: | SP-A2, COLEC5 |
Name Aliases: | surfactant, pulmonary-associated protein A2A |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:10799 | RefSeq IDs: | NM_001098668 |
Entrez Gene ID: | 729238 | Ensembl Gene ID: | ENSG00000185303 |
VEGA IDs: | UniProt ID: | Q8IWL1 | |
UCSC ID: | uc001kal.3 | OMIM ID: | 178642 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS41540.1 |
SFTPA2 is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
Products for SFTPA2 gene
Catalog | Product Name | Application | Company |
GFS:E00714 | surfactant protein A2; ELISA kit | ELISA | n/a |
GFS:A00714 | surfactant protein A2; Anti | ANTIBODIES | n/a |
GFS:P00714 | surfactant protein A2; Protien | Protien | n/a |