Symbol: Name: ID: |
STAR steroidogenic acute regulatory protein GFS:1249 |
Gene name: | STAR |
Chromosome: | 8p11.2 |
Previous Symbols: | |
Previous Names: | steroidogenic acute regulator |
Aliases: | StAR, STARD1 |
Name Aliases: | StAR-related lipid transfer (START) domain containing 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:102760 | Rat Genome Database ID: | RGD:3770 |
HGNC ID: | HGNC:11359 | RefSeq IDs: | NM_000349 |
Entrez Gene ID: | 6770 | Ensembl Gene ID: | ENSG00000147465 |
VEGA IDs: | UniProt ID: | P49675 | |
UCSC ID: | uc003xkv.1 | OMIM ID: | 600617 |
Pubmed: | PMID7761400 | ||
CCDS IDs: | CCDSCCDS6102.1 |
The protein encoded by the STAR gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
Products for STAR gene
Catalog | Product Name | Application | Company |
GFS:E01249 | steroidogenic acute regulatory protein; ELISA kit | ELISA | n/a |
GFS:A01249 | steroidogenic acute regulatory protein; Anti | ANTIBODIES | n/a |
GFS:P01249 | steroidogenic acute regulatory protein; Protien | Protien | n/a |