Symbol: Name: ID: |
STARD6 StAR-related lipid transfer (START) domain containing 6 GFS:6956 |
Gene name: | STARD6 |
Chromosome: | 18q21.2 |
Previous Symbols: | |
Previous Names: | START domain containing 6 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2156774 | Rat Genome Database ID: | |
HGNC ID: | HGNC:18066 | RefSeq IDs: | NM_139171 |
Entrez Gene ID: | 147323 | Ensembl Gene ID: | ENSG00000174448 |
VEGA IDs: | OTTHUMG00000132702 | UniProt ID: | P59095 |
UCSC ID: | uc010xdt.1 | OMIM ID: | 607051 |
Pubmed: | PMID12011452 | ||
CCDS IDs: | CCDSCCDS11955.1 |
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD6 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008].
Function: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols (By similarity).
Products for STARD6 gene
Catalog | Product Name | Application | Company |
GFS:E06956 | StAR-related lipid transfer (START) domain containing 6; ELISA kit | ELISA | n/a |
GFS:A06956 | StAR-related lipid transfer (START) domain containing 6; Anti | ANTIBODIES | n/a |
GFS:P06956 | StAR-related lipid transfer (START) domain containing 6; Protien | Protien | n/a |