Symbol: Name: ID: |
STC2 stanniocalcin 2 GFS:1264 |
Gene name: | STC2 |
Chromosome: | 5q35.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | STC-2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1316731 | Rat Genome Database ID: | RGD:621777 |
HGNC ID: | HGNC:11374 | RefSeq IDs: | NM_003714 |
Entrez Gene ID: | 8614 | Ensembl Gene ID: | ENSG00000113739 |
VEGA IDs: | OTTHUMG00000130542 | UniProt ID: | O76061 |
UCSC ID: | uc003mco.1 | OMIM ID: | 603665 |
Pubmed: | PMID9723890 PMID 9753616 | ||
CCDS IDs: | CCDSCCDS4388.1 |
Stanniocalcin-2 is a protein that in humans is encoded by the STC2 gene.This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Has an anti-hypocalcemic action on calcium and phosphate homeostasis.
Products for STC2 gene
Catalog | Product Name | Application | Company |
GFS:E01264 | stanniocalcin 2; ELISA kit | ELISA | n/a |
GFS:A01264 | stanniocalcin 2; Anti | ANTIBODIES | n/a |
GFS:P01264 | stanniocalcin 2; Protien | Protien | n/a |