Symbol: Name: ID: |
STC1 stanniocalcin 1 GFS:1263 |
Gene name: | STC1 |
Chromosome: | 8p22-p12 |
Previous Symbols: | STC |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:109131 | Rat Genome Database ID: | RGD:621776 |
HGNC ID: | HGNC:11373 | RefSeq IDs: | NM_003155 |
Entrez Gene ID: | 6781 | Ensembl Gene ID: | ENSG00000159167 |
VEGA IDs: | OTTHUMG00000097853 | UniProt ID: | P52823 |
UCSC ID: | uc003xdw.1 | OMIM ID: | 601185 |
Pubmed: | PMID9480753 | ||
CCDS IDs: | CCDSCCDS6043.1 |
Stanniocalcin-1 is a protein that in humans is encoded by the STC1 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia.
Products for STC1 gene
Catalog | Product Name | Application | Company |
GFS:E01263 | stanniocalcin 1; ELISA kit | ELISA | n/a |
GFS:A01263 | stanniocalcin 1; Anti | ANTIBODIES | n/a |
GFS:P01263 | stanniocalcin 1; Protien | Protien | n/a |