Symbol: Name: ID: |
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) GFS:3606 |
Gene name: | SMPD3 |
Chromosome: | 16q22.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NSMASE2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1927578 | Rat Genome Database ID: | RGD:619754 |
HGNC ID: | HGNC:14240 | RefSeq IDs: | NM_018667 |
Entrez Gene ID: | 55512 | Ensembl Gene ID: | ENSG00000103056 |
VEGA IDs: | OTTHUMG00000137559 | UniProt ID: | Q9NY59 |
UCSC ID: | uc002ewa.2 | OMIM ID: | 605777 |
Pubmed: | PMID10823942 | ||
CCDS IDs: | CCDSCCDS10867.1 |
Sphingomyelin phosphodiesterase 3 is an enzyme that in humans is encoded by the SMPD3 gene.
Function: Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.
Products for SMPD3 gene
Catalog | Product Name | Application | Company |
GFS:E03606 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II); ELISA kit | ELISA | n/a |
GFS:A03606 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II); Anti | ANTIBODIES | n/a |
GFS:P03606 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II); Protien | Protien | n/a |