Symbol: Name: ID: |
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 GFS:1434 |
Gene name: | SERPINA7 |
Chromosome: | Xq21-q22 |
Previous Symbols: | TBG |
Previous Names: | serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
Aliases: | |
Name Aliases: | thyroxin-binding globulin, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3041197 | Rat Genome Database ID: | RGD:619833 |
HGNC ID: | HGNC:11583 | RefSeq IDs: | NM_000354 |
Entrez Gene ID: | 6906 | Ensembl Gene ID: | ENSG00000123561 |
VEGA IDs: | OTTHUMG00000022144 | UniProt ID: | P05543 |
UCSC ID: | uc004eme.1 | OMIM ID: | 314200 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS14518.1 |
Thyroxine-binding globulin (TBG) binds thyroid hormone in circulation. There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3#-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for SERPINA7 gene
Catalog | Product Name | Application | Company |
GFS:E01434 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; ELISA kit | ELISA | n/a |
GFS:A01434 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; Anti | ANTIBODIES | n/a |
GFS:P01434 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; Protien | Protien | n/a |