Symbol: Name: ID: |
STK4 serine/threonine kinase 4 GFS:1293 |
Gene name: | STK4 |
Chromosome: | 20q11.2-q13.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | MST1, KRS2, YSK3 |
Name Aliases: | mammalian sterile 20-like 1, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1929004 | Rat Genome Database ID: | RGD:1312035 |
HGNC ID: | HGNC:11408 | RefSeq IDs: | NM_006282 |
Entrez Gene ID: | 6789 | Ensembl Gene ID: | ENSG00000101109 |
VEGA IDs: | OTTHUMG00000033059 | UniProt ID: | Q13043 |
UCSC ID: | uc002xnb.2 | OMIM ID: | 604965 |
Pubmed: | PMID8816758 PMID 9545236 PMID 11517310 | ||
CCDS IDs: | CCDSCCDS13341.1 |
Serine/threonine-protein kinase 4 is an enzyme that in humans is encoded by the STK4 gene. The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for STK4 gene
Catalog | Product Name | Application | Company |
GFS:E01293 | serine/threonine kinase 4; ELISA kit | ELISA | n/a |
GFS:A01293 | serine/threonine kinase 4; Anti | ANTIBODIES | n/a |
GFS:P01293 | serine/threonine kinase 4; Protien | Protien | n/a |