Symbol: Name: ID: |
SPINK1 serine peptidase inhibitor, Kazal type 1 GFS:1135 |
Gene name: | SPINK1 |
Chromosome: | 5q32 |
Previous Symbols: | |
Previous Names: | serine protease inhibitor, Kazal type 1 |
Aliases: | Spink3, PCTT, PSTI, TATI |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:106202 | Rat Genome Database ID: | RGD:708468 |
HGNC ID: | HGNC:11244 | RefSeq IDs: | NM_003122 |
Entrez Gene ID: | 6690 | Ensembl Gene ID: | ENSG00000164266 |
VEGA IDs: | OTTHUMG00000129730 | UniProt ID: | P00995 |
UCSC ID: | uc003los.2 | OMIM ID: | 167790 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS4286.1 |
Pancreatic secretory trypsin inhibitor (PSTI) also known as serine protease inhibitor Kazal-type 1 (SPINK1) or tumor-associated trypsin inhibitor (TATI) is a protein that in humans is encoded by the SPINK1 gene. The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas.
Products for SPINK1 gene
Catalog | Product Name | Application | Company |
GFS:E01135 | serine peptidase inhibitor, Kazal type 1; ELISA kit | ELISA | n/a |
GFS:A01135 | serine peptidase inhibitor, Kazal type 1; Anti | ANTIBODIES | n/a |
GFS:P01135 | serine peptidase inhibitor, Kazal type 1; Protien | Protien | n/a |