Symbol: Name: ID: |
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) GFS:765 |
Gene name: | SHMT2 |
Chromosome: | 12q12-q14 |
Previous Symbols: | SHMT |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1277989 | Rat Genome Database ID: | RGD:1308582 |
HGNC ID: | HGNC:10852 | RefSeq IDs: | NM_001166356 |
Entrez Gene ID: | 6472 | Ensembl Gene ID: | ENSG00000182199 |
VEGA IDs: | UniProt ID: | P34897 | |
UCSC ID: | uc001snf.1 | OMIM ID: | 138450 |
Pubmed: | PMID8999870 | ||
CCDS IDs: | CCDSCCDS8934.1 |
SHMT2 encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Products for SHMT2 gene
Catalog | Product Name | Application | Company |
GFS:E00765 | serine hydroxymethyltransferase 2 (mitochondrial); ELISA kit | ELISA | n/a |
GFS:A00765 | serine hydroxymethyltransferase 2 (mitochondrial); Anti | ANTIBODIES | n/a |
GFS:P00765 | serine hydroxymethyltransferase 2 (mitochondrial); Protien | Protien | n/a |