Symbol: Name: ID: |
SHMT1 serine hydroxymethyltransferase 1 (soluble) GFS:763 |
Gene name: | SHMT1 |
Chromosome: | 17p11.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CSHMT, SHMT, MGC15229, MGC24556 |
Name Aliases: | cytoplasmic serine hydroxymethyltransferase, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98299 | Rat Genome Database ID: | RGD:1312011 |
HGNC ID: | HGNC:10850 | RefSeq IDs: | NM_004169 |
Entrez Gene ID: | 6470 | Ensembl Gene ID: | ENSG00000176974 |
VEGA IDs: | OTTHUMG00000059094 | UniProt ID: | P34896 |
UCSC ID: | uc002gta.2 | OMIM ID: | 182144 |
Pubmed: | PMID8505317 | ||
CCDS IDs: | CCDSCCDS11196.1 CCDS CCDS11197.1 |
SHMT1 encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq].
Products for SHMT1 gene
Catalog | Product Name | Application | Company |
GFS:E00763 | serine hydroxymethyltransferase 1 (soluble); ELISA kit | ELISA | n/a |
GFS:A00763 | serine hydroxymethyltransferase 1 (soluble); Anti | ANTIBODIES | n/a |
GFS:P00763 | serine hydroxymethyltransferase 1 (soluble); Protien | Protien | n/a |