Symbol: Name: ID: |
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) GFS:223 |
Gene name: | ROBO2 |
Chromosome: | 3p12.3 |
Previous Symbols: | |
Previous Names: | roundabout (axon guidance receptor, Drosophila) homolog 2 |
Aliases: | KIAA1568 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1890110 | Rat Genome Database ID: | |
HGNC ID: | HGNC:10250 | RefSeq IDs: | NM_001128929 |
Entrez Gene ID: | 6092 | Ensembl Gene ID: | ENSG00000185008 |
VEGA IDs: | OTTHUMG00000158935 | UniProt ID: | Q9HCK4 |
UCSC ID: | uc003dpy.3 | OMIM ID: | 602431 |
Pubmed: | PMID9458045 | ||
CCDS IDs: | CCDSCCDS43109.1 |
Roundabout, axon guidance receptor, homolog 2 belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq].
Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development
Products for ROBO2 gene
Catalog | Product Name | Application | Company |
GFS:E00223 | roundabout, axon guidance receptor, homolog 2 (Drosophila); ELISA kit | ELISA | n/a |
GFS:A00223 | roundabout, axon guidance receptor, homolog 2 (Drosophila); Anti | ANTIBODIES | n/a |
GFS:P00223 | roundabout, axon guidance receptor, homolog 2 (Drosophila); Protien | Protien | n/a |