Symbol: Name: ID: |
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) GFS:222 |
Gene name: | ROBO1 |
Chromosome: | 3p12.3 |
Previous Symbols: | |
Previous Names: | roundabout (axon guidance receptor, Drosophila) homolog 1 |
Aliases: | DUTT1, FLJ21882, SAX3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1274781 | Rat Genome Database ID: | RGD:61941 |
HGNC ID: | HGNC:10249 | RefSeq IDs: | NM_001145845 |
Entrez Gene ID: | 6091 | Ensembl Gene ID: | ENSG00000169855 |
VEGA IDs: | OTTHUMG00000158843 | UniProt ID: | Q9Y6N7 |
UCSC ID: | uc003dqe.2 | OMIM ID: | 602430 |
Pubmed: | PMID9458045 PMID 9608531 | ||
CCDS IDs: | CCDSCCDS46872.1 |
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Products for ROBO1 gene
Catalog | Product Name | Application | Company |
GFS:E00222 | roundabout, axon guidance receptor, homolog 1 (Drosophila); ELISA kit | ELISA | n/a |
GFS:A00222 | roundabout, axon guidance receptor, homolog 1 (Drosophila); Anti | ANTIBODIES | n/a |
GFS:P00222 | roundabout, axon guidance receptor, homolog 1 (Drosophila); Protien | Protien | n/a |