Symbol: Name: ID: |
RRM1 ribonucleotide reductase M1 GFS:397 |
Gene name: | RRM1 |
Chromosome: | 11p15.5 |
Previous Symbols: | |
Previous Names: | ribonucleotide reductase M1 polypeptide |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98180 | Rat Genome Database ID: | RGD:1598288 |
HGNC ID: | HGNC:10451 | RefSeq IDs: | NM_001033 |
Entrez Gene ID: | 6240 | Ensembl Gene ID: | ENSG00000167325 |
VEGA IDs: | OTTHUMG00000133361 | UniProt ID: | P23921 |
UCSC ID: | uc001lyw.3 | OMIM ID: | 180410 |
Pubmed: | PMID7557993 | ||
CCDS IDs: | CCDSCCDS7750.1 |
RRM1 encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for RRM1 gene
Catalog | Product Name | Application | Company |
GFS:E00397 | ribonucleotide reductase M1; ELISA kit | ELISA | n/a |
GFS:A00397 | ribonucleotide reductase M1; Anti | ANTIBODIES | n/a |
GFS:P00397 | ribonucleotide reductase M1; Protien | Protien | n/a |