Symbol: Name: ID: |
POFUT2 protein O-fucosyltransferase 2 GFS:3966 |
Gene name: | POFUT2 |
Chromosome: | 21q22.3 |
Previous Symbols: | C21orf80 |
Previous Names: | chromosome 21 open reading frame 80 |
Aliases: | KIAA0958, FUT13 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1916863 | Rat Genome Database ID: | RGD:1307334 |
HGNC ID: | HGNC:14683 | RefSeq IDs: | NM_015227 |
Entrez Gene ID: | 23275 | Ensembl Gene ID: | ENSG00000186866 |
VEGA IDs: | OTTHUMG00000084874 | UniProt ID: | Q9Y2G5 |
UCSC ID: | uc002zhc.2 | OMIM ID: | 610249 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS13719.1 CCDS CCDS13721.1 |
Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008].
Function: Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats.
Products for POFUT2 gene
Catalog | Product Name | Application | Company |
GFS:E03966 | protein O-fucosyltransferase 2; ELISA kit | ELISA | n/a |
GFS:A03966 | protein O-fucosyltransferase 2; Anti | ANTIBODIES | n/a |
GFS:P03966 | protein O-fucosyltransferase 2; Protien | Protien | n/a |