Symbol: Name: ID: |
POFUT1 protein O-fucosyltransferase 1 GFS:4269 |
Gene name: | POFUT1 |
Chromosome: | 20q11 |
Previous Symbols: | |
Previous Names: | |
Aliases: | O-FUT, O-Fuc-T, KIAA0180, FUT12 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2153207 | Rat Genome Database ID: | RGD:1303001 |
HGNC ID: | HGNC:14988 | RefSeq IDs: | NM_015352 |
Entrez Gene ID: | 23509 | Ensembl Gene ID: | ENSG00000101346 |
VEGA IDs: | OTTHUMG00000133268 | UniProt ID: | Q9H488 |
UCSC ID: | uc002wxp.2 | OMIM ID: | 607491 |
Pubmed: | PMID9023546 PMID 9525914 | ||
CCDS IDs: | CCDSCCDS13198.1 CCDS CCDS13199.1 |
This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Function: Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in EGF domains. Plays a crucial role in Notch signaling.
Products for POFUT1 gene
Catalog | Product Name | Application | Company |
GFS:E04269 | protein O-fucosyltransferase 1; ELISA kit | ELISA | n/a |
GFS:A04269 | protein O-fucosyltransferase 1; Anti | ANTIBODIES | n/a |
GFS:P04269 | protein O-fucosyltransferase 1; Protien | Protien | n/a |