Symbol: Name: ID: |
PROK2 prokineticin 2 GFS:7305 |
Gene name: | PROK2 |
Chromosome: | 3p21.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | PK2, BV8, MIT1, KAL4 |
Name Aliases: | protein Bv8 homolog |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1354178 | Rat Genome Database ID: | RGD:620280 |
HGNC ID: | HGNC:18455 | RefSeq IDs: | NM_001126128 |
Entrez Gene ID: | 60675 | Ensembl Gene ID: | ENSG00000163421 |
VEGA IDs: | OTTHUMG00000158809 | UniProt ID: | Q9HC23 |
UCSC ID: | uc003dpa.3 | OMIM ID: | 607002 |
Pubmed: | PMID11054548 PMID 11259612 | ||
CCDS IDs: | CCDSCCDS2916.1 CCDS CCDS46868.1 |
This gene encodes a protein expressed in the suprachiasmatic nucleus (SCN) circadian clock that may function as the output component of the circadian clock. The secreted form of the encoded protein may also serve as a chemoattractant for neuronal precursor cells in the olfactory bulb. Proteins from other vertebrates which are similar to this gene product were isolated based on homology to snake venom and secretions from frog skin, and have been shown to have diverse functions. Mutations in this gene are associated with Kallmann syndrome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function: May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.
Products for PROK2 gene
Catalog | Product Name | Application | Company |
GFS:E07305 | prokineticin 2; ELISA kit | ELISA | n/a |
GFS:A07305 | prokineticin 2; Anti | ANTIBODIES | n/a |
GFS:P07305 | prokineticin 2; Protien | Protien | n/a |