Symbol: Name: ID: |
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 GFS:6583 |
Gene name: | NUDT10 |
Chromosome: | Xp11.22-p11.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | DIPP3a, hDIPP3alpha |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2147931 | Rat Genome Database ID: | RGD:1564763 |
HGNC ID: | HGNC:17621 | RefSeq IDs: | NM_153183 |
Entrez Gene ID: | 170685 | Ensembl Gene ID: | ENSG00000122824 |
VEGA IDs: | OTTHUMG00000021530 | UniProt ID: | Q8NFP7 |
UCSC ID: | uc004dph.2 | OMIM ID: | 300527 |
Pubmed: | PMID12105228 | ||
CCDS IDs: | CCDSCCDS35278.1 |
NUDT10 belongs to a subgroup of phosphohydrolases that preferentially attack diphosphoinositol polyphosphates (Hidaka et al., 2002 [PubMed 12105228]).[supplied by OMIM, Mar 2008]. Sequence Note: removed 2 bases from the 5' end that did not align to the reference genome assembly.
Function: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Products for NUDT10 gene
Catalog | Product Name | Application | Company |
GFS:E06583 | nudix (nucleoside diphosphate linked moiety X)-type motif 10; ELISA kit | ELISA | n/a |
GFS:A06583 | nudix (nucleoside diphosphate linked moiety X)-type motif 10; Anti | ANTIBODIES | n/a |
GFS:P06583 | nudix (nucleoside diphosphate linked moiety X)-type motif 10; Protien | Protien | n/a |