| Symbol: Name: ID: |
NKD2 naked cuticle homolog 2 (Drosophila) GFS:6140 |
| Gene name: | NKD2 |
| Chromosome: | 5p15.3 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | Naked2 |
| Name Aliases: | naked cuticle-2, |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1919543 | Rat Genome Database ID: | RGD:1311459 |
| HGNC ID: | HGNC:17046 | RefSeq IDs: | NM_033120 |
| Entrez Gene ID: | 85409 | Ensembl Gene ID: | ENSG00000145506 |
| VEGA IDs: | OTTHUMG00000090348 | UniProt ID: | Q969F2 |
| UCSC ID: | uc003jbt.1 | OMIM ID: | 607852 |
| Pubmed: | PMID11356022 PMID 11604995 | ||
| CCDS IDs: | CCDSCCDS3859.1 | ||
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM, Jun 2003].
Function: Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity (By similarity). Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells.
Products for NKD2 gene
| Catalog | Product Name | Application | Company |
| GFS:E06140 | naked cuticle homolog 2 (Drosophila); ELISA kit | ELISA | n/a |
| GFS:A06140 | naked cuticle homolog 2 (Drosophila); Anti | ANTIBODIES | n/a |
| GFS:P06140 | naked cuticle homolog 2 (Drosophila); Protien | Protien | n/a |
