Symbol: Name: ID: |
NKD1 naked cuticle homolog 1 (Drosophila) GFS:6139 |
Gene name: | NKD1 |
Chromosome: | 16q12.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2135954 | Rat Genome Database ID: | RGD:1308491 |
HGNC ID: | HGNC:17045 | RefSeq IDs: | NM_033119 |
Entrez Gene ID: | 85407 | Ensembl Gene ID: | ENSG00000140807 |
VEGA IDs: | OTTHUMG00000133169 | UniProt ID: | Q969G9 |
UCSC ID: | uc002egg.1 | OMIM ID: | 607851 |
Pubmed: | PMID11356022 | ||
CCDS IDs: | CCDSCCDS10743.1 |
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM, Jun 2003]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Function: Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity.
Products for NKD1 gene
Catalog | Product Name | Application | Company |
GFS:E06139 | naked cuticle homolog 1 (Drosophila); ELISA kit | ELISA | n/a |
GFS:A06139 | naked cuticle homolog 1 (Drosophila); Anti | ANTIBODIES | n/a |
GFS:P06139 | naked cuticle homolog 1 (Drosophila); Protien | Protien | n/a |