Symbol: Name: ID: |
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 GFS:6087 |
Gene name: | MLLT11 |
Chromosome: | 1q21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | AF1Q |
Name Aliases: | ALL1 fused gene from chromosome 1q |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1929671 | Rat Genome Database ID: | RGD:1305525 |
HGNC ID: | HGNC:16997 | RefSeq IDs: | NM_006818 |
Entrez Gene ID: | 10962 | Ensembl Gene ID: | ENSG00000213190 |
VEGA IDs: | OTTHUMG00000035160 | UniProt ID: | Q13015 |
UCSC ID: | uc001ewq.2 | OMIM ID: | 604684 |
Pubmed: | PMID7833468 | ||
CCDS IDs: | CCDSCCDS982.1 |
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008].
Products for MLLT11 gene
Catalog | Product Name | Application | Company |
GFS:E06087 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11; ELISA kit | ELISA | n/a |
GFS:A06087 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11; Anti | ANTIBODIES | n/a |
GFS:P06087 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11; Protien | Protien | n/a |