Symbol: Name: ID: |
MMP26 matrix metallopeptidase 26 GFS:3614 |
Gene name: | MMP26 |
Chromosome: | 11p15 |
Previous Symbols: | |
Previous Names: | matrix metalloproteinase 26 |
Aliases: | endometase, MGC126590, MGC126592 |
Name Aliases: | matrilysin 2 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:14249 | RefSeq IDs: | NM_021801 |
Entrez Gene ID: | 56547 | Ensembl Gene ID: | ENSG00000167346 |
VEGA IDs: | OTTHUMG00000066442 | UniProt ID: | Q9NRE1 |
UCSC ID: | uc001lzv.2 | OMIM ID: | 605470 |
Pubmed: | PMID10801841 PMID 10824119 | ||
CCDS IDs: | CCDSCCDS7752.1 |
Matrix metalloproteinase-26 also known as matrilysin-2 and endometase is an enzyme that in humans is encoded by the MMP26 gene.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin and alpha-1 proteinase inhibitor. Is also able to activates progelatinase B.
Products for MMP26 gene
Catalog | Product Name | Application | Company |
GFS:E03614 | matrix metallopeptidase 26; ELISA kit | ELISA | n/a |
GFS:A03614 | matrix metallopeptidase 26; Anti | ANTIBODIES | n/a |
GFS:P03614 | matrix metallopeptidase 26; Protien | Protien | n/a |