Symbol: Name: ID: |
LPIN2 lipin 2 GFS:3780 |
Gene name: | LPIN2 |
Chromosome: | 18p |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0249 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1891341 | Rat Genome Database ID: | RGD:1304588 |
HGNC ID: | HGNC:14450 | RefSeq IDs: | NM_014646 |
Entrez Gene ID: | 9663 | Ensembl Gene ID: | ENSG00000101577 |
VEGA IDs: | OTTHUMG00000131508 | UniProt ID: | Q92539 |
UCSC ID: | uc002klo.2 | OMIM ID: | 605519 |
Pubmed: | PMID11138012 PMID 9039502 | ||
CCDS IDs: | CCDSCCDS11829.1 |
Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism (By similarity).
Products for LPIN2 gene
Catalog | Product Name | Application | Company |
GFS:E03780 | lipin 2; ELISA kit | ELISA | n/a |
GFS:A03780 | lipin 2; Anti | ANTIBODIES | n/a |
GFS:P03780 | lipin 2; Protien | Protien | n/a |