Symbol: Name: ID: |
LAT2 linker for activation of T cells family, member 2 GFS:2514 |
Gene name: | LAT2 |
Chromosome: | 7q11.23 |
Previous Symbols: | WBSCR15, WBSCR5 |
Previous Names: | Williams-Beuren syndrome chromosome region 5 |
Aliases: | WSCR5, HSPC046, LAB, NTAL |
Name Aliases: | linker for activation of B cells, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1926479 | Rat Genome Database ID: | RGD:631397 |
HGNC ID: | HGNC:12749 | RefSeq IDs: | NM_014146 |
Entrez Gene ID: | 7462 | Ensembl Gene ID: | ENSG00000086730 |
VEGA IDs: | OTTHUMG00000130151 | UniProt ID: | Q9GZY6 |
UCSC ID: | uc003uai.2 | OMIM ID: | 605719 |
Pubmed: | PMID8812460 PMID 12514734 | ||
CCDS IDs: | CCDSCCDS5566.2 |
Linker for activation of T-cells family member 2 is a protein that in humans is encoded by the LAT2 gene.
This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. [provided by RefSeq].
Function: Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Products for LAT2 gene
Catalog | Product Name | Application | Company |
GFS:E02514 | linker for activation of T cells family, member 2; ELISA kit | ELISA | n/a |
GFS:A02514 | linker for activation of T cells family, member 2; Anti | ANTIBODIES | n/a |
GFS:P02514 | linker for activation of T cells family, member 2; Protien | Protien | n/a |