| Symbol: Name: ID: |
KREMEN1 kringle containing transmembrane protein 1 GFS:6544 |
| Gene name: | KREMEN1 |
| Chromosome: | 22q12.1 |
| Previous Symbols: | KREMEN |
| Previous Names: | kringle containing transmembrane protein |
| Aliases: | KRM1 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1933988 | Rat Genome Database ID: | RGD:620789 |
| HGNC ID: | HGNC:17550 | RefSeq IDs: | NM_001039570 |
| Entrez Gene ID: | 83999 | Ensembl Gene ID: | ENSG00000183762 |
| VEGA IDs: | OTTHUMG00000030987 | UniProt ID: | Q96MU8 |
| UCSC ID: | uc011akm.1 | OMIM ID: | 609898 |
| Pubmed: | PMID11267660 | ||
| CCDS IDs: | CCDSCCDS43000.1 CCDS CCDS13849.1 | ||
Kremen protein 1 is a protein that in humans is encoded by the KREMEN1 gene.
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008].
Function: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity).
Products for KREMEN1 gene
| Catalog | Product Name | Application | Company |
| GFS:E06544 | kringle containing transmembrane protein 1; ELISA kit | ELISA | n/a |
| GFS:A06544 | kringle containing transmembrane protein 1; Anti | ANTIBODIES | n/a |
| GFS:P06544 | kringle containing transmembrane protein 1; Protien | Protien | n/a |
