| Symbol: Name: ID: |
IL33 interleukin 33 GFS:5156 |
| Gene name: | IL33 |
| Chromosome: | 9p24.1 |
| Previous Symbols: | C9orf26 |
| Previous Names: | chromosome 9 open reading frame 26 (NF-HEV) |
| Aliases: | DVS27, DKFZp586H0523, NF-HEV |
| Name Aliases: | DVS27-related protein |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1924375 | Rat Genome Database ID: | RGD:1311155 |
| HGNC ID: | HGNC:16028 | RefSeq IDs: | NM_001199640 |
| Entrez Gene ID: | 90865 | Ensembl Gene ID: | ENSG00000137033 |
| VEGA IDs: | OTTHUMG00000019516 | UniProt ID: | O95760 |
| UCSC ID: | uc003zju.1 | OMIM ID: | 608678 |
| Pubmed: | PMID10566975 PMID 12819012 | ||
| CCDS IDs: | CCDSCCDS6468.1 | ||
IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010 [PubMed 20926795]).[supplied by OMIM, Jan 2011].
Function: Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T helper type 2-associated cytokines.
Products for IL33 gene
| Catalog | Product Name | Application | Company |
| GFS:E05156 | interleukin 33; ELISA kit | ELISA | n/a |
| GFS:A05156 | interleukin 33; Anti | ANTIBODIES | n/a |
| GFS:P05156 | interleukin 33; Protien | Protien | n/a |
