Symbol: Name: ID: |
IL25 interleukin 25 GFS:3264 |
Gene name: | IL25 |
Chromosome: | 14q11.2 |
Previous Symbols: | IL17E |
Previous Names: | interleukin 17E |
Aliases: | IL-25, IL-17E |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2155888 | Rat Genome Database ID: | RGD:1561632 |
HGNC ID: | HGNC:13765 | RefSeq IDs: | NM_022789 |
Entrez Gene ID: | 64806 | Ensembl Gene ID: | ENSG00000166090 |
VEGA IDs: | OTTHUMG00000028749 | UniProt ID: | Q9H293 |
UCSC ID: | uc001wjq.2 | OMIM ID: | 605658 |
Pubmed: | PMID11058597 PMID 11754819 | ||
CCDS IDs: | CCDSCCDS9597.1 CCDS CCDS45086.1 |
Interleukin-25 (IL-25) is a protein that in humans is encoded by the IL25 gene.
The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].
Function: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.
Products for IL25 gene
Catalog | Product Name | Application | Company |
GFS:E03264 | interleukin 25; ELISA kit | ELISA | n/a |
GFS:A03264 | interleukin 25; Anti | ANTIBODIES | n/a |
GFS:P03264 | interleukin 25; Protien | Protien | n/a |