Symbol: Name: ID: |
IL32 interleukin 32 GFS:5917 |
Gene name: | IL32 |
Chromosome: | 16p13.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NK4, TAIF, TAIFb, TAIFd |
Name Aliases: | natural killer cell transcript 4 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:16830 | RefSeq IDs: | NM_001012631 |
Entrez Gene ID: | 9235 | Ensembl Gene ID: | ENSG00000008517 |
VEGA IDs: | UniProt ID: | P24001 | |
UCSC ID: | uc002ctn.2 | OMIM ID: | 606001 |
Pubmed: | PMID1729377 PMID 9653642 | ||
CCDS IDs: | CCDSCCDS32377.1 CCDS CCDS32378.1 CCDS CCDS32379.1 CCDS CCDS45394.1 |
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Function: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK.
Products for IL32 gene
Catalog | Product Name | Application | Company |
GFS:E05917 | interleukin 32; ELISA kit | ELISA | n/a |
GFS:A05917 | interleukin 32; Anti | ANTIBODIES | n/a |
GFS:P05917 | interleukin 32; Protien | Protien | n/a |