Symbol: Name: ID: |
IL29 interleukin 29 (interferon, lambda 1) GFS:7230 |
Gene name: | IL29 |
Chromosome: | 19q13.13 |
Previous Symbols: | |
Previous Names: | interleukin 29 |
Aliases: | IL-29, IFNL1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:18363 | RefSeq IDs: | NM_172140 |
Entrez Gene ID: | 282618 | Ensembl Gene ID: | ENSG00000182393 |
VEGA IDs: | UniProt ID: | Q8IU54 | |
UCSC ID: | uc002okv.2 | OMIM ID: | 607403 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS12531.1 |
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
Products for IL29 gene
Catalog | Product Name | Application | Company |
GFS:E07230 | interleukin 29 (interferon, lambda 1); ELISA kit | ELISA | n/a |
GFS:A07230 | interleukin 29 (interferon, lambda 1); Anti | ANTIBODIES | n/a |
GFS:P07230 | interleukin 29 (interferon, lambda 1); Protien | Protien | n/a |