Symbol: Name: ID: |
IL26 interleukin 26 GFS:6211 |
Gene name: | IL26 |
Chromosome: | 12q15 |
Previous Symbols: | |
Previous Names: | |
Aliases: | AK155, IL-26 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:17119 | RefSeq IDs: | NM_018402 |
Entrez Gene ID: | 55801 | Ensembl Gene ID: | ENSG00000111536 |
VEGA IDs: | OTTHUMG00000135184 | UniProt ID: | Q9NPH9 |
UCSC ID: | uc001stx.1 | OMIM ID: | 605679 |
Pubmed: | PMID10729163 PMID 11528524 | ||
CCDS IDs: | CCDSCCDS8981.1 |
This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
Products for IL26 gene
Catalog | Product Name | Application | Company |
GFS:E06211 | interleukin 26; ELISA kit | ELISA | n/a |
GFS:A06211 | interleukin 26; Anti | ANTIBODIES | n/a |
GFS:P06211 | interleukin 26; Protien | Protien | n/a |