Symbol: Name: ID: |
IL17RC interleukin 17 receptor C GFS:7224 |
Gene name: | IL17RC |
Chromosome: | 3p25.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | IL17-RL |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2159336 | Rat Genome Database ID: | RGD:1306392 |
HGNC ID: | HGNC:18358 | RefSeq IDs: | NM_001203263 |
Entrez Gene ID: | 84818 | Ensembl Gene ID: | ENSG00000163702 |
VEGA IDs: | OTTHUMG00000128648 | UniProt ID: | Q8NAC3 |
UCSC ID: | uc003bua.2 | OMIM ID: | 610925 |
Pubmed: | PMID11706037 | ||
CCDS IDs: | CCDSCCDS2590.1 CCDS CCDS2591.2 CCDS CCDS46746.1 |
Interleukin-17 receptor C is a protein that in humans is encoded by the IL17RC gene.
This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011].
Products for IL17RC gene
Catalog | Product Name | Application | Company |
GFS:E07224 | interleukin 17 receptor C; ELISA kit | ELISA | n/a |
GFS:A07224 | interleukin 17 receptor C; Anti | ANTIBODIES | n/a |
GFS:P07224 | interleukin 17 receptor C; Protien | Protien | n/a |