Symbol: Name: ID: |
IL1F9 interleukin 1 family, member 9 GFS:4896 |
Gene name: | IL1F9 |
Chromosome: | 2q12-q21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | IL-1H1, IL-1RP2, IL-1F9 |
Name Aliases: | interleukin-1 homolog 1, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2449929 | Rat Genome Database ID: | RGD:1563019 |
HGNC ID: | HGNC:15741 | RefSeq IDs: | NM_019618 |
Entrez Gene ID: | 56300 | Ensembl Gene ID: | ENSG00000136688 |
VEGA IDs: | OTTHUMG00000131336 | UniProt ID: | Q9NZH8 |
UCSC ID: | uc002tio.1 | OMIM ID: | 605542 |
Pubmed: | PMID10860666 PMID 10744718 PMID 11991722 PMID 11991723 | ||
CCDS IDs: | CCDSCCDS2108.1 |
Interleukin-1 family member 9 is a protein that in humans is encoded by the IL1F9 gene.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.
Products for IL1F9 gene
Catalog | Product Name | Application | Company |
GFS:E04896 | interleukin 1 family, member 9; ELISA kit | ELISA | n/a |
GFS:A04896 | interleukin 1 family, member 9; Anti | ANTIBODIES | n/a |
GFS:P04896 | interleukin 1 family, member 9; Protien | Protien | n/a |