Symbol: Name: ID: |
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor GFS:6207 |
Gene name: | HIF1AN |
Chromosome: | 10q24 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FLJ20615, DKFZp762F1811, FLJ22027, FIH1 |
Name Aliases: | Peptide-aspartate beta-dioxygenase |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2442345 | Rat Genome Database ID: | RGD:1308281 |
HGNC ID: | HGNC:17113 | RefSeq IDs: | NM_017902 |
Entrez Gene ID: | 55662 | Ensembl Gene ID: | ENSG00000166135 |
VEGA IDs: | OTTHUMG00000018911 | UniProt ID: | Q9NWT6 |
UCSC ID: | uc001krj.3 | OMIM ID: | 606615 |
Pubmed: | PMID11641274 | ||
CCDS IDs: | CCDSCCDS7498.1 |
Hypoxia-inducible factor 1-alpha inhibitor is a protein that in humans is encoded by the HIF1AN gene.
Function: Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.
Products for HIF1AN gene
Catalog | Product Name | Application | Company |
GFS:E06207 | hypoxia inducible factor 1, alpha subunit inhibitor; ELISA kit | ELISA | n/a |
GFS:A06207 | hypoxia inducible factor 1, alpha subunit inhibitor; Anti | ANTIBODIES | n/a |
GFS:P06207 | hypoxia inducible factor 1, alpha subunit inhibitor; Protien | Protien | n/a |