Symbol: Name: ID: |
HES7 hairy and enhancer of split 7 (Drosophila) GFS:5108 |
Gene name: | HES7 |
Chromosome: | 17p13.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | bHLHb37 |
Name Aliases: | bHLH factor Hes7 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2135679 | Rat Genome Database ID: | RGD:1305914 |
HGNC ID: | HGNC:15977 | RefSeq IDs: | NM_001165967 |
Entrez Gene ID: | 84667 | Ensembl Gene ID: | ENSG00000179111 |
VEGA IDs: | UniProt ID: | Q9BYE0 | |
UCSC ID: | uc002gkc.2 | OMIM ID: | 608059 |
Pubmed: | PMID11260262 | ||
CCDS IDs: | CCDSCCDS42258.1 |
This gene encodes a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].
Function: Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity).
Products for HES7 gene
Catalog | Product Name | Application | Company |
GFS:E05108 | hairy and enhancer of split 7 (Drosophila); ELISA kit | ELISA | n/a |
GFS:A05108 | hairy and enhancer of split 7 (Drosophila); Anti | ANTIBODIES | n/a |
GFS:P05108 | hairy and enhancer of split 7 (Drosophila); Protien | Protien | n/a |