Symbol: Name: ID: |
EDDM3A epididymal protein 3A GFS:6066 |
Gene name: | EDDM3A |
Chromosome: | 14q11.1 |
Previous Symbols: | FAM12A |
Previous Names: | family with sequence similarity 12, member A |
Aliases: | HE3-ALPHA |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:16978 | RefSeq IDs: | NM_006683 |
Entrez Gene ID: | 10876 | Ensembl Gene ID: | ENSG00000181562 |
VEGA IDs: | OTTHUMG00000029581 | UniProt ID: | Q14507 |
UCSC ID: | uc001vyc.2 | OMIM ID: | 611580 |
Pubmed: | PMID7514008 | ||
CCDS IDs: | CCDSCCDS9556.1 |
Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq, Jul 2008].
Function: Possible function in sperm maturation.
Products for EDDM3A gene
Catalog | Product Name | Application | Company |
GFS:E06066 | epididymal protein 3A; ELISA kit | ELISA | n/a |
GFS:A06066 | epididymal protein 3A; Anti | ANTIBODIES | n/a |
GFS:P06066 | epididymal protein 3A; Protien | Protien | n/a |