| Symbol: Name: ID: |
ECE2 endothelin converting enzyme 2 GFS:2916 |
| Gene name: | ECE2 |
| Chromosome: | 3q27.1 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | KIAA0604, MGC2408 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1101356 | Rat Genome Database ID: | RGD:1303039 |
| HGNC ID: | HGNC:13275 | RefSeq IDs: | NM_001037324 |
| Entrez Gene ID: | 9718 | Ensembl Gene ID: | ENSG00000145194 |
| VEGA IDs: | OTTHUMG00000150551 | UniProt ID: | O60344 |
| UCSC ID: | uc003fni.3 | OMIM ID: | 610145 |
| Pubmed: | PMID11718899 | ||
| CCDS IDs: | CCDSCCDS3255.1 CCDS CCDS33899.1 CCDS CCDS3256.2 CCDS CCDS43179.1 CCDS CCDS46969.1 | ||
Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family (Lorenzo et al., 2001 [PubMed 11718899]).[supplied by OMIM].
Function: Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.
Products for ECE2 gene
| Catalog | Product Name | Application | Company |
| GFS:E02916 | endothelin converting enzyme 2; ELISA kit | ELISA | n/a |
| GFS:A02916 | endothelin converting enzyme 2; Anti | ANTIBODIES | n/a |
| GFS:P02916 | endothelin converting enzyme 2; Protien | Protien | n/a |
