Symbol: Name: ID: |
DYNLT3 dynein, light chain, Tctex-type 3 GFS:1512 |
Gene name: | DYNLT3 |
Chromosome: | Xp21 |
Previous Symbols: | TCTE1L |
Previous Names: | t-complex-associated-testis-expressed 1-like |
Aliases: | TCTEX1L |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1914367 | Rat Genome Database ID: | RGD:1549755 |
HGNC ID: | HGNC:11694 | RefSeq IDs: | NM_006520 |
Entrez Gene ID: | 6990 | Ensembl Gene ID: | ENSG00000165169 |
VEGA IDs: | OTTHUMG00000033172 | UniProt ID: | P51808 |
UCSC ID: | uc004dds.2 | OMIM ID: | 300302 |
Pubmed: | PMID8004092 | ||
CCDS IDs: | CCDSCCDS14243.1 |
Dynein, light chain, Tctex-type 3, also known as DYNLT3, is a protein which in humans is encoded by the DYNLT3 gene. This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity).
Products for DYNLT3 gene
Catalog | Product Name | Application | Company |
GFS:E01512 | dynein, light chain, Tctex-type 3; ELISA kit | ELISA | n/a |
GFS:A01512 | dynein, light chain, Tctex-type 3; Anti | ANTIBODIES | n/a |
GFS:P01512 | dynein, light chain, Tctex-type 3; Protien | Protien | n/a |