Symbol: Name: ID: |
CCR2 chemokine (C-C motif) receptor 2 GFS:5158 |
Gene name: | CCR2 |
Chromosome: | 3p21 |
Previous Symbols: | CMKBR2 |
Previous Names: | |
Aliases: | CC-CKR-2, CKR2, MCP-1-R, CD192, FLJ78302 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | RGD:620876 | |
HGNC ID: | HGNC:1603 | RefSeq IDs: | NM_001123041 |
Entrez Gene ID: | 729230 | Ensembl Gene ID: | ENSG00000121807 |
VEGA IDs: | OTTHUMG00000156466 | UniProt ID: | P41597 |
UCSC ID: | uc003cpm.3 | OMIM ID: | 601267 |
Pubmed: | PMID8146186 | ||
CCDS IDs: | CCDSCCDS43078.1 CCDS CCDS46813.1 |
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].
Function: Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
Products for CCR2 gene
Catalog | Product Name | Application | Company |
GFS:E05158 | chemokine (C-C motif) receptor 2; ELISA kit | ELISA | n/a |
GFS:A05158 | chemokine (C-C motif) receptor 2; Anti | ANTIBODIES | n/a |
GFS:P05158 | chemokine (C-C motif) receptor 2; Protien | Protien | n/a |