Symbol: Name: ID: |
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) GFS:5327 |
Gene name: | CCT6A |
Chromosome: | 7p11.2 |
Previous Symbols: | CCT6 |
Previous Names: | |
Aliases: | TTCP20, TCPZ, Cctz, HTR3, TCP20 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107943 | Rat Genome Database ID: | RGD:1304763 |
HGNC ID: | HGNC:1620 | RefSeq IDs: | NM_001009186 |
Entrez Gene ID: | 908 | Ensembl Gene ID: | ENSG00000146731 |
VEGA IDs: | OTTHUMG00000022842 | UniProt ID: | P40227 |
UCSC ID: | uc003trl.1 | OMIM ID: | 104613 |
Pubmed: | PMID1352881 PMID 8034610 | ||
CCDS IDs: | CCDSCCDS5523.1 CCDS CCDS34640.1 |
T-complex protein 1 subunit zeta is a protein that in humans is encoded by the CCT6A gene.
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq, Jun 2010].
Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Products for CCT6A gene
Catalog | Product Name | Application | Company |
GFS:E05327 | chaperonin containing TCP1, subunit 6A (zeta 1); ELISA kit | ELISA | n/a |
GFS:A05327 | chaperonin containing TCP1, subunit 6A (zeta 1); Anti | ANTIBODIES | n/a |
GFS:P05327 | chaperonin containing TCP1, subunit 6A (zeta 1); Protien | Protien | n/a |