Symbol: Name: ID: |
CCT4 chaperonin containing TCP1, subunit 4 (delta) GFS:5295 |
Gene name: | CCT4 |
Chromosome: | 2p15 |
Previous Symbols: | |
Previous Names: | |
Aliases: | Cctd |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:104689 | Rat Genome Database ID: | RGD:727937 |
HGNC ID: | HGNC:1617 | RefSeq IDs: | NM_006430 |
Entrez Gene ID: | 10575 | Ensembl Gene ID: | ENSG00000115484 |
VEGA IDs: | OTTHUMG00000152166 | UniProt ID: | P50991 |
UCSC ID: | uc002sbo.2 | OMIM ID: | 605142 |
Pubmed: | PMID9819444 | ||
CCDS IDs: | CCDSCCDS33206.1 |
T-complex protein 1 subunit delta is a protein that in humans is encoded by the CCT4 gene.
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.
Products for CCT4 gene
Catalog | Product Name | Application | Company |
GFS:E05295 | chaperonin containing TCP1, subunit 4 (delta); ELISA kit | ELISA | n/a |
GFS:A05295 | chaperonin containing TCP1, subunit 4 (delta); Anti | ANTIBODIES | n/a |
GFS:P05295 | chaperonin containing TCP1, subunit 4 (delta); Protien | Protien | n/a |