Symbol: Name: ID: |
CACNB2 calcium channel, voltage-dependent, beta 2 subunit GFS:3454 |
Gene name: | CACNB2 |
Chromosome: | 10p12 |
Previous Symbols: | MYSB, CACNLB2 |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:894644 | Rat Genome Database ID: | RGD:67385 |
HGNC ID: | HGNC:1402 | RefSeq IDs: | NM_000724 |
Entrez Gene ID: | 783 | Ensembl Gene ID: | ENSG00000165995 |
VEGA IDs: | OTTHUMG00000017764 | UniProt ID: | Q08289 |
UCSC ID: | uc001ipr.2 | OMIM ID: | 600003 |
Pubmed: | PMID9254841 PMID 8494331 | ||
CCDS IDs: | CCDSCCDS7125.1 CCDS CCDS7126.1 CCDS CCDS7127.1 CCDS CCDS7128.1 CCDS CCDS7129.1 CCDS CCDS41493.1 CCDS CCDS41494.1 |
Voltage-dependent L-type calcium channel subunit beta-2 is a protein that in humans is encoded by the CACNB2 gene.
This gene encodes a subunit of a voltage-dependent calcium channel protein which is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome which is an autoimmune disorder. Mutations in this gene are associated with Brugada symdrome. Alternatively spliced variants have been identified for this gene. [provided by RefSeq, Nov 2009].
Function: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Products for CACNB2 gene
Catalog | Product Name | Application | Company |
GFS:E03454 | calcium channel, voltage-dependent, beta 2 subunit; ELISA kit | ELISA | n/a |
GFS:A03454 | calcium channel, voltage-dependent, beta 2 subunit; Anti | ANTIBODIES | n/a |
GFS:P03454 | calcium channel, voltage-dependent, beta 2 subunit; Protien | Protien | n/a |