Symbol: Name: ID: |
CACNB1 calcium channel, voltage-dependent, beta 1 subunit GFS:3444 |
Gene name: | CACNB1 |
Chromosome: | 17q21-q22 |
Previous Symbols: | CACNLB1 |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:102522 | Rat Genome Database ID: | RGD:68382 |
HGNC ID: | HGNC:1401 | RefSeq IDs: | NM_000723 |
Entrez Gene ID: | 782 | Ensembl Gene ID: | ENSG00000067191 |
VEGA IDs: | OTTHUMG00000133217 | UniProt ID: | Q02641 |
UCSC ID: | uc002hrm.1 | OMIM ID: | 114207 |
Pubmed: | PMID8381767 PMID 8395940 | ||
CCDS IDs: | CCDSCCDS11334.1 CCDS CCDS42311.1 CCDS CCDS45665.1 |
Voltage-dependent L-type calcium channel subunit beta-1 is a protein that in humans is encoded by the CACNB1 gene.
The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
Function: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Products for CACNB1 gene
Catalog | Product Name | Application | Company |
GFS:E03444 | calcium channel, voltage-dependent, beta 1 subunit; ELISA kit | ELISA | n/a |
GFS:A03444 | calcium channel, voltage-dependent, beta 1 subunit; Anti | ANTIBODIES | n/a |
GFS:P03444 | calcium channel, voltage-dependent, beta 1 subunit; Protien | Protien | n/a |