Symbol: Name: ID: |
BEST4 bestrophin 4 GFS:6200 |
Gene name: | BEST4 |
Chromosome: | 1p33-p32.3 |
Previous Symbols: | VMD2L2 |
Previous Names: | vitelliform macular dystrophy 2-like 2 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3663793 | Rat Genome Database ID: | |
HGNC ID: | HGNC:17106 | RefSeq IDs: | NM_153274 |
Entrez Gene ID: | 266675 | Ensembl Gene ID: | ENSG00000142959 |
VEGA IDs: | OTTHUMG00000008488 | UniProt ID: | Q8NFU0 |
UCSC ID: | uc001cmm.2 | OMIM ID: | 607336 |
Pubmed: | PMID12032738 PMID 16702355 | ||
CCDS IDs: | CCDSCCDS514.1 |
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon. [provided by RefSeq, Jul 2008].
Function: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
Products for BEST4 gene
Catalog | Product Name | Application | Company |
GFS:E06200 | bestrophin 4; ELISA kit | ELISA | n/a |
GFS:A06200 | bestrophin 4; Anti | ANTIBODIES | n/a |
GFS:P06200 | bestrophin 4; Protien | Protien | n/a |