| Symbol: Name: ID: |
BEST2 bestrophin 2 GFS:6201 |
| Gene name: | BEST2 |
| Chromosome: | 19p13.2-p13.12 |
| Previous Symbols: | VMD2L1 |
| Previous Names: | vitelliform macular dystrophy 2-like 1 |
| Aliases: | FLJ20132 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2387588 | Rat Genome Database ID: | RGD:1305377 |
| HGNC ID: | HGNC:17107 | RefSeq IDs: | NM_017682 |
| Entrez Gene ID: | 54831 | Ensembl Gene ID: | ENSG00000039987 |
| VEGA IDs: | UniProt ID: | Q8NFU1 | |
| UCSC ID: | uc002mux.2 | OMIM ID: | 607335 |
| Pubmed: | PMID12032738 PMID 16912113 | ||
| CCDS IDs: | CCDSCCDS42506.1 | ||
Bestrophin-2 is a protein that in humans is encoded by the BEST2 gene.
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008].
Function: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
Products for BEST2 gene
| Catalog | Product Name | Application | Company |
| GFS:E06201 | bestrophin 2; ELISA kit | ELISA | n/a |
| GFS:A06201 | bestrophin 2; Anti | ANTIBODIES | n/a |
| GFS:P06201 | bestrophin 2; Protien | Protien | n/a |
